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pH dependent regulator of desquamation

 
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PostPosted: Tue 16:15, 05 Nov 2013    Post subject: pH dependent regulator of desquamation

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The lymphoepithelial Kazal type 5 [url=http://www.anepf.fr]doudoune moncler[/url] serine protease inhibitor (LEKTI), encoded by the serine protease inhibitor Kazal type 5 (SPINK5) gene, is a particularly important, pH dependent regulator of desquamation (M [url=http://www.plain-peek.de]barbour[/url] et al., 1999; Deraison et al., 2007). LEKTI is composed of 15 potential serine proteinase inhibitory domains, at least four of which have confirmed activity against members of the KLK family, including KLK5, KLK7, and KLK14 (Borgo et al., 2007; Deraison et al., 2007). LEKTI is expressed in the granular layer of the epidermis, and delivered to the SG interface in lamellar bodies (Ishida Yamamoto et al., 2005).
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